T-cell directed differentiation from iPSCs directed towards CAR T cell production and cancer treatment, and endothelial cell and clinical efficacy of its secretome in a range of clinical indications

Theme 2: Advanced Materials and Manufacturing

Prof. Laurence Meagher
A/Prof. Tracy Heng
Prof. Mibel Aguilar
A/Prof. Travis Klein

Three PhD projects will cover these topics, which are currently being finalised with industry partners. There projects are surface modification/material related and relate to the expansion of cells for manufacturing purposes, giving great skills that could be broadly applied in biotechnology, a growth industry. These projects will provide working experience with small Australian companies and present a range of opportunities. One is directed towards T-cell directed differentiation from iPSCs, directed towards CAR T cell production and cancer treatment and the other to a specific type of endothelial cell and clinical efficacy of its secretome (soluble factors, exosomes etc) in a range of clinical indications.

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