High-throughput 3D bioprinting of the tumour microenvironment

Theme 3: Tissue engineering

Dr. Laura Bray

A/Prof. Yi-Chin Toh

Prof. Gail Risbridger

This project aims to develop methods and materials to facilitate the high-throughput 3D printing of complex tumour microenvironments with defined mechanical and biochemical properties incorporating cancer, stromal, and endothelial cells, as well as tissue- and pathology-specific extracellular matrix components. The system will be applied to systematically study the influence of variations in the biochemical, biological, and mechanical properties on cancer-associated pathological processes using Design of Experiment (DoE) principles.

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