Archives: Projects

Development of a novel biodegradable scaffold for the repair of injured or degenerate cartilaginous tissues including the intervertebral disc

Theme 3: Tissue Engineering A/Prof. Jessica Frith Cartilage tissue possesses a limited regenerative potential and degeneration of the cartilage is a common problem following injury or with aging. This includes degeneration of the cartilaginous tissue of the intervertebral disc, which is a leading cause of lower back pain. Current therapies cannot restore the function of …

Development of a novel biodegradable scaffold for the repair of injured or degenerate cartilaginous tissues including the intervertebral disc Read More »

Analysing the Entrepreneurial Ecosystem in the Australian Tissue Engineering and Regenerative Medicine Industry

Theme 4: Value chain and commercialisation Prof. Dietmar W Hutmacher Prof. Martin Obschonka This project will explore the challenges associated with entrepreneurial activity commercializing tissue engineering and regenerative medicine developed at research institutions with a focus on Australia and aiming to benchmark against Canada, US, Europe, South Korea and Japan. An entrepreneurial process perspective will …

Analysing the Entrepreneurial Ecosystem in the Australian Tissue Engineering and Regenerative Medicine Industry Read More »

In vivo assessment of BoneFlo® system in an ovine model of tibial critical-sized defect

Theme 3: Tissue Engineering Technologies Dr. Laura BrayDr. Siamak SaifzadehDr. Roland SteckProf. Dietmar Hutmacher This project seeks to develop advanced manufacturing and injection moulding of biomaterials to optimise surface properties. The project involves the development of smart technologies, including web-based pre-operative planning tools (automated segmentation of CT data, automated application of a statistical shape model, …

In vivo assessment of BoneFlo® system in an ovine model of tibial critical-sized defect Read More »

Supply chain optimisation

Theme 4: Value chain and commercialisation Prof. Amrik SohalProf. Uwe DulleckProf. Dietmar Hutmacher The project will seek to understand supply chain inventory flow, storage and quality control metrics from trial to bedside in current cell therapy research pathways, including transit times, handover points, dwell points, container transit/storage temperature boundaries and cell viability measures. These metrics …

Supply chain optimisation Read More »

Business model innovations

Theme 4: Value chain and commercialisation Prof. Amrik Sohal Prof. Dietmar W Hutmacher Prof. Uwe Dulleck This project analyses two distinctive approaches of commercialisation in regenerative medicine; the centralised global approach, and a distributed localised approach. It will involve a comparison of these approaches, together with multiple hybrids of these models that foster local industrial growth. …

Business model innovations Read More »

Determinants of effective surgeon and patient interactions in regenerative medicine 

Theme 4: Value chain and commercialisation Prof. Uwe Dulleck Dr. Laura BrayDr. Stephen Whyte Prof. Rebekah Russell-Bennett Prof. Dietmar Hutmacher This project will involve analysis of the economic incentives that face surgeons as advisors and providers of the service, and patients, identifying necessary market conditions, and institutions that ensure efficient provision of the service. It …

Determinants of effective surgeon and patient interactions in regenerative medicine  Read More »

Scaffold-cell based breast tissue engineering

Theme 3: Tissue Engineering Technologies Prof. Dietmar HutmacherDr. Jacqui McGovernDr. Roland SteckDr. Laura Bray Dr. Siamak Saifzadeh This project includes studies focusing on the development and in vitro biocompatibility of biomaterials to determine long-term maintenance and growth of normal breast cells and tissues on prepared next-generation 3D printed scaffolds in static and bioreactor culture. Confocal …

Scaffold-cell based breast tissue engineering Read More »

Organ perfusion for transplant mechanism using cell-based regenerative products

Theme 3: Tissue Engineering Technologies A/Prof. Rebecca Lim This project will investigate the potential for perfusion and stem cells to regenerate and repair and/or rejuvenate organs through the application of cellular therapies or their exosomes prior to transplantation. Amniotic membrane epithelial cells, which have shown great potential in eliciting protective and regenerative effects in lungs …

Organ perfusion for transplant mechanism using cell-based regenerative products Read More »

T-cell directed differentiation from iPSCs directed towards CAR T cell production and cancer treatment, and endothelial cell and clinical efficacy of its secretome in a range of clinical indications

Theme 2: Advanced Materials and Manufacturing Prof. Laurence MeagherA/Prof. Tracy HengProf. Mibel AguilarA/Prof. Travis Klein Three PhD projects will cover these topics, which are currently being finalised with industry partners. There projects are surface modification/material related and relate to the expansion of cells for manufacturing purposes, giving great skills that could be broadly applied in …

T-cell directed differentiation from iPSCs directed towards CAR T cell production and cancer treatment, and endothelial cell and clinical efficacy of its secretome in a range of clinical indications Read More »