Archives: Projects

Smart technologies for customisable bone regeneration

Theme 3: Tissue Engineering Technologies Dr. Laura BrayDr. Siamak SaifzadehDr. Roland SteckProf. Dietmar Hutmacher This project seeks to develop advanced manufacturing and injection moulding of biomaterials to optimise surface properties. The project involves the development of smart technologies, including web-based pre-operative planning tools (automated segmentation of CT data, automated application of a statistical shape model, …

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Supply chain optimisation

Theme 4: Value chain and commercialisation Prof. Amrik Sohal Prof. Uwe Dulleck Prof. Dietmar Hutmacher The project will seek to understand supply chain inventory flow, storage and quality control metrics from trial to bedside in current cell therapy research pathways, including transit times, handover points, dwell points, container transit/storage temperature boundaries and cell viability measures. …

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Business model innovations

Theme 4: Value chain and commercialisation Prof. Dietmar Hutmacher Prof. Dietmar Hutmacher Prof. Amrik Sohal Prof. Uwe Dulleck This project analyses two distinctive approaches of commercialisation in regenerative medicine; the centralised global approach, and a distributed localised approach. It will involve a comparison of these approaches, together with multiple hybrids of these models that foster …

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Determinants of effective surgeon and patient interactions in regenerative medicine 

Theme 4: Value chain and commercialisation Prof. Uwe Dulleck Dr. Stephen Whyte This project will involve analysis of the economic incentives that face surgeons as advisors and providers of the service, and patients, identifying necessary market conditions, and institutions that ensure efficient provision of the service. It will involve artefactual field experiments using a two-sided …

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Scaffold-cell based breast tissue engineering

Theme 3: Tissue Engineering Technologies Prof. Dietmar Hutmacher Dr. Jacqui McGovern Dr. Roland Steck Dr. Laura Bray This project includes studies focusing on the development and in vitro biocompatibility of biomaterials to determine long-term maintenance and growth of normal breast cells and tissues on prepared next-generation 3D printed scaffolds in static and bioreactor culture. Confocal …

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Organ perfusion for transplant mechanism using cell-based regenerative products

Theme 3: Tissue Engineering Technologies A/Prof. Rebecca Lim This project will investigate the potential for perfusion and stem cells to regenerate and repair and/or rejuvenate organs through the application of cellular therapies or their exosomes prior to transplantation. Amniotic membrane epithelial cells, which have shown great potential in eliciting protective and regenerative effects in lungs …

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Materials and processes for optimised, scalable manufacture of stem cells for therapeutic applications

Theme 2: Advanced Materials and Manufacturing Prof. Laurence Meagher A/Prof. Tracy Heng Prof. Mibel Aguilar A/Prof. Travis Klein In this project, we will apply novel chemistries, biomimicry and methodologies to develop polymer based, chemically-defined and scalable material solutions for manufacturing. These materials will be optimised around maximising yield and potency in connection with bioreactor design …

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Biosensors for cell quality control

Theme 1: Engineering process efficiencies Prof. Nico Voelcker A/Prof. Tim Dargaville Dr Roey Elnathan This project involves the development of a disposable offline cartridge based on electrochemical and microelectromechanical system sensors to measure cell culture conditions via detection of micronutrients and metabolite panels. Piezoelectric and electrochemical immunosensors will then be created to determine residual lentivirus …

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MEMS based pH tracking devices for cell product quality control

Theme 1: Engineering process efficiencies Prof. Nico Voelcker A/Prof. Tim Dargaville Dr Simon Corrie This project involves the development of resonating bean microelectromechanical systems (MEMS) and electrochemical pH sensor chips suitable for inclusion in cell culture flasks or storage vials that communicate with a handheld reader and provides a signal when the cell culture medium …

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